Establishing a Framework for Pragmatic Trial Operations (PTOps): A Learning Health System Playbook
This dataset/document outlines the Pragmatic Trial Operations (PTOps) framework, a Learning Health System (LHS) playbook developed by the University of Wisconsin-Madison (UW) Institute for Clinical and Translational Research (ICTR) in partnership with UW Health and Marshfield Clinic. The PTOps framework is designed to bridge the gap between clinical innovation and operational reality by "learning from what we do and doing what we learn". It utilizes rapid Plan-Do-Check-Act (PDCA) cycles to integrate research-grade analytics into operationally driven pilots, ensuring that clinical interventions align with strategic health system priorities.
Authors
- Graham Wills
- Felice Resnik (ORCID: https://orcid.org/0000-0003-1494-1357)
- Becky Kohler
- Elizabeth S. Burnside (ORCID: https://orcid.org/0000-0002-6600-435X)
- Stacy Rasmussen (ORCID: https://orcid.org/0009-0009-2202-0911)
- Heidi Twedt (ORCID: https://orcid.org/0000-0002-7091-0152)
- Cherodeep Goswami (ORCID: https://orcid.org/0009-0008-9805-4694)
- Majid Afshar
- Kirsten Abramson (ORCID: https://orcid.org/0000-0001-8491-3138)
- Anthony Stordalen
- Sarah Brzozowski
- John Long (ORCID: https://orcid.org/0009-0007-2939-9130)
- Caitlin Voegele
- Joel Gordon (ORCID: https://orcid.org/0000-0001-7619-9384)
- Tina Shah
- Michael Oberst (ORCID: https://orcid.org/0000-0003-1720-6702)
- Thomas Brazelton (ORCID: https://orcid.org/0000-0003-2840-3285)
- Ann Wieben
- Josie Hinktzke (ORCID: https://orcid.org/0009-0001-6840-1340)
- Brian Patterson (ORCID: https://orcid.org/0000-0002-4584-3808)
- Jason Anthony Dambach (ORCID: https://orcid.org/0009-0001-2354-230X)
- Jenn Hankwitz
- Jann Pfaff
- Frank Liao (ORCID: https://orcid.org/0000-0002-7577-7530)
- Kayla Lemmon
- Mary Ryan Baumann (ORCID: https://orcid.org/0000-0002-9137-1549)
- Anne Gravel Sullivan (ORCID: https://orcid.org/0009-0009-7972-6907)
- Leigh Ann Mrotek (ORCID: https://orcid.org/0000-0001-6559-934X)
- Chelsey Langer
- David Kunstman (ORCID: https://orcid.org/0009-0003-2816-2175)
- Peter Kleinschmidt (ORCID: https://orcid.org/0000-0003-1672-6845)
- Mariah Quinn (ORCID: https://orcid.org/0000-0001-7534-739X)
Institutions
- University of Wisconsin–Madison (US)
- University of Wisconsin Health (US)
Publication Details
- Journal
- Zenodo (CERN European Organization for Nuclear Research)
- Published
- 2026-05-11
- DOI
- https://doi.org/10.5281/zenodo.20128376
- Primary Topic
- Health Policy Implementation Science
- Type
- article
- Field-Weighted Citation Impact
- 0.00