Anterior Fibromuscular Stroma‐Preserving Anteroposterior Dissection <scp>HoLEP</scp> Reduces Day‐1 Incontinence: A Retrospective Cohort Study

OBJECTIVES: To determine whether anterior fibromuscular stroma (AFS) preservation within an anteroposterior (AP) HoLEP platform independently reduces ultra-early postoperative incontinence. METHODS: We retrospectively analyzed consecutive HoLEP cases (April 2019-June 2025) performed by a single surgeon. Of 719 procedures, 272 consecutive cases using a standardized AP platform were included and classified into conventional AP-HoLEP (CON, n = 60), mucosal incision-first AP-HoLEP (MI, n = 180), and AFS-preserving AP-HoLEP (AFS, n = 32). The primary endpoint was Day-1 incontinence, defined as any objective leakage (> 0 mL) within 24 h after catheter removal on Postoperative Day 2. Multivariable logistic regression was used to identify independent predictors. RESULTS: Day-1 incontinence occurred in 55% (33/60) of CON, 58% (104/180) of MI, and 25% (8/32) of AFS cases (p = 0.003). In multivariable analysis, AFS preservation was independently associated with lower odds of Day-1 incontinence versus CON (odds ratio [OR], 0.30; 95% confidence interval [CI], 0.11-0.80; p = 0.016), whereas MI was not (OR, 1.14; 95% CI, 0.62-2.11; p = 0.680). Perioperative safety outcomes were comparable, with low rates of Clavien-Dindo ≥ III events. CONCLUSIONS: Within an AP-HoLEP platform, AFS preservation was associated with improved Day-1 continence without compromising safety, supporting ventral-support preservation as a key lever for ultra-early continence recovery.

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Journal
International Journal of Urology
Published
2026-05-01
DOI
https://doi.org/10.1111/iju.70492
Primary Topic
Pelvic floor disorders treatments
Type
article
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article

Anterior Fibromuscular Stroma‐Preserving Anteroposterior Dissection HoLEP Reduces Day‐1 Incontinence: A Retrospective Cohort Study

Takato Nishino, Kazuhiro Ohwaki, Koki Tominaga, Masaki Shimbo et al.
International Journal of Urology
Pelvic floor disorders treatments
article

Anterior Fibromuscular Stroma‐Preserving Anteroposterior Dissection HoLEP Reduces Day‐1 Incontinence: A Retrospective Cohort Study

Takato Nishino, Kazuhiro Ohwaki, Koki Tominaga, Masaki Shimbo, Takeru Morishige, Masayuki Sano, Tomohiko Oguchi, Kazutaka Narimoto, Kazunori Hattori, Fumiyasu Endo, Ken Fujita
article en

Abstract

OBJECTIVES: To determine whether anterior fibromuscular stroma (AFS) preservation within an anteroposterior (AP) HoLEP platform independently reduces ultra-early postoperative incontinence. METHODS: We retrospectively analyzed consecutive HoLEP cases (April 2019-June 2025) performed by a single surgeon. Of 719 procedures, 272 consecutive cases using a standardized AP platform were included and classified into conventional AP-HoLEP (CON, n = 60), mucosal incision-first AP-HoLEP (MI, n = 180), and AFS-preserving AP-HoLEP (AFS, n = 32). The primary endpoint was Day-1 incontinence, defined as any objective leakage (> 0 mL) within 24 h after catheter removal on Postoperative Day 2. Multivariable logistic regression was used to identify independent predictors. RESULTS: Day-1 incontinence occurred in 55% (33/60) of CON, 58% (104/180) of MI, and 25% (8/32) of AFS cases (p = 0.003). In multivariable analysis, AFS preservation was independently associated with lower odds of Day-1 incontinence versus CON (odds ratio [OR], 0.30; 95% confidence interval [CI], 0.11-0.80; p = 0.016), whereas MI was not (OR, 1.14; 95% CI, 0.62-2.11; p = 0.680). Perioperative safety outcomes were comparable, with low rates of Clavien-Dindo ≥ III events. CONCLUSIONS: Within an AP-HoLEP platform, AFS preservation was associated with improved Day-1 continence without compromising safety, supporting ventral-support preservation as a key lever for ultra-early continence recovery.

International Journal of UrologyVol. 33(5)
St. Luke's International Hospital (JP), Teikyo University (JP)
Openalex Percentile: Top 5%
Pelvic floor disorders treatments
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