<scp>PHACE</scp> (S) Syndrome Minus the H: A Case of Possible <scp>PHACE</scp> (S) Syndrome Without an Infantile Hemangioma

A 4-month-old, full-term girl was referred for evaluation of a supraumbilical raphe and an anomalous aortic arch. Further work up for PHACE(S) syndrome was pursued, despite the absence of a cutaneous infantile hemangioma (IH), which identified hypoplastic and dysplastic cerebral vasculature. We present this case to raise awareness of possible PHACE(S) syndrome even in children without cutaneous IHs and the importance of recognizing supraumbilical raphe as a sentinel finding.

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Publication Details

Journal
Pediatric Dermatology
Published
2026-05-10
DOI
https://doi.org/10.1111/pde.70236
Primary Topic
Vascular Malformations and Hemangiomas
Type
article
Field-Weighted Citation Impact
0.00
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article

PHACE (S) Syndrome Minus the H: A Case of Possible PHACE (S) Syndrome Without an Infantile Hemangioma

Vikash S. Oza, Margaret F. Cote, Evan G. Stein
Pediatric Dermatology
Vascular Malformations and Hemangiomas
article

PHACE (S) Syndrome Minus the H: A Case of Possible PHACE (S) Syndrome Without an Infantile Hemangioma

Vikash S. Oza, Margaret F. Cote, Evan G. Stein
article en

Abstract

A 4-month-old, full-term girl was referred for evaluation of a supraumbilical raphe and an anomalous aortic arch. Further work up for PHACE(S) syndrome was pursued, despite the absence of a cutaneous infantile hemangioma (IH), which identified hypoplastic and dysplastic cerebral vasculature. We present this case to raise awareness of possible PHACE(S) syndrome even in children without cutaneous IHs and the importance of recognizing supraumbilical raphe as a sentinel finding.

Pediatric Dermatology
New York University (US)
Gender equality
Openalex Percentile: Top 5%
Vascular Malformations and Hemangiomas
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