Survival Outcomes in Middle-aged and Older Patients with Advanced Heart Failure: A Propensity-Matched Analysis of HeartMate 3 LVAD and Heart Transplant Using MOMENTUM 3 and UNOS Registry
Heart failure (HF) increases in prevalence with age. For advanced HF patients, both durable left ventricular assist devices (LVAD) and heart transplantation (HT) can improve longevity and quality of life. However, comparing optimal outcomes amongst the two therapies in middle-aged and older patients who are eligible for both remains controversial.
Authors
- Finn Gustafsson (ORCID: https://orcid.org/0000-0003-2144-341X)
- F. Lee
- I Gosev
- Ulrich P. Jorde (ORCID: https://orcid.org/0000-0002-9476-6466)
- Ilan Richter (ORCID: https://orcid.org/0000-0001-9358-0056)
- M Yuzefpolskaya
- John D Henderson
- Stavros G. Drakos
- Gabriel T. Sayer
- Kevin J. Clerkin
- Daniel J. Goldstein
- Manreet K. Kanwar (ORCID: https://orcid.org/0000-0002-7280-5268)
- Joseph C. Cleveland
- Mandeep R. Mehra (ORCID: https://orcid.org/0000-0001-8683-7044)
- Nir Uriel (ORCID: https://orcid.org/0000-0003-2301-3587)
- Paolo C. Colombo
Institutions
- Brigham and Women's Hospital (US)
- Albert Einstein College of Medicine (US)
- Montefiore Medical Center (US)
- University of Utah (US)
- Columbia University Irving Medical Center (US)
- University of Rochester Medical Center (US)
- University of Chicago (US)
- Utah Department of Health (US)
- Abbott Fund (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- JACC Heart Failure
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1016/j.jchf.2026.103159
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Heart, Lung, and Blood Institute