Development of Renal‐Clearable NIR‐II Fluorescent Probes via Hydrophilicity Tuning for Imaging of Chronic Kidney Disease

≈ 530 nm), we further investigated the underlying mechanisms of renal injury in CKD. Our findings elucidate how functional impairment in the glomeruli leads to abnormal retention of exogenous substances within renal tissues. These results position CS-CY5-PEG as a versatile platform for noninvasive renal diagnostics and nephrotoxicity evaluation in preclinical research.

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Publication Details

Journal
Small
Published
2026-05-10
DOI
https://doi.org/10.1002/smll.202514874
Primary Topic
Nanoplatforms for cancer theranostics
Type
article
Field-Weighted Citation Impact
0.00

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article

Development of Renal‐Clearable NIR‐II Fluorescent Probes via Hydrophilicity Tuning for Imaging of Chronic Kidney Disease

Yuxin Xie, Tian‐Bing Ren, Ling Shi, J Zhou et al.
Small
Nanoplatforms for cancer theranostics
article

Development of Renal‐Clearable NIR‐II Fluorescent Probes via Hydrophilicity Tuning for Imaging of Chronic Kidney Disease

Yuxin Xie, Tian‐Bing Ren, Ling Shi, J Zhou, Lin Yuan, Xinyu Zhao
article en

Abstract

≈ 530 nm), we further investigated the underlying mechanisms of renal injury in CKD. Our findings elucidate how functional impairment in the glomeruli leads to abnormal retention of exogenous substances within renal tissues. These results position CS-CY5-PEG as a versatile platform for noninvasive renal diagnostics and nephrotoxicity evaluation in preclinical research.

Small
Hunan University of Traditional Chinese Medicine (CN), Hunan University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Hunan Province
Openalex Percentile: Top 8%
Nanoplatforms for cancer theranostics
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