Incidental Detection of Miliary Tuberculosis During Laparoscopic Cholecystectomy: A Case Report

Miliary tuberculosis is a rare but potentially severe form of disseminated tuberculosis resulting from the hematogenous spread of Mycobacterium tuberculosis, leading to the widespread granulomatous involvement of multiple organ systems. Peritoneal tuberculosis represents an uncommon manifestation of extrapulmonary tuberculosis and often presents with vague and nonspecific clinical features, frequently mimicking intra-abdominal malignancies and posing a significant diagnostic challenge. We report the case of a 24-year-old immunocompetent female patient who presented with symptomatic cholelithiasis and underwent elective laparoscopic cholecystectomy. Intraoperatively, multiple whitish, millet-sized nodules were incidentally identified over the peritoneum, liver surface, and omentum. Histopathological examination confirmed caseating granulomatous inflammation consistent with tuberculosis. The patient was subsequently started on anti-tubercular therapy and showed good clinical improvement on follow-up. This case highlights the importance of intraoperative vigilance, the role of laparoscopy, and the necessity of histopathological confirmation in differentiating tuberculosis from malignancy in endemic regions.

Authors

Publication Details

Journal
Cureus
Published
2026-05-10
DOI
https://doi.org/10.7759/cureus.108596
Primary Topic
Diagnosis and treatment of tuberculosis
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Incidental Detection of Miliary Tuberculosis During Laparoscopic Cholecystectomy: A Case Report

Saddiqa Rahman, Md. Akbar Khan, Nasheeta Usman
Cureus
Diagnosis and treatment of tuberculosis
article

Incidental Detection of Miliary Tuberculosis During Laparoscopic Cholecystectomy: A Case Report

Saddiqa Rahman, Md. Akbar Khan, Nasheeta Usman
article en

Abstract

Miliary tuberculosis is a rare but potentially severe form of disseminated tuberculosis resulting from the hematogenous spread of Mycobacterium tuberculosis, leading to the widespread granulomatous involvement of multiple organ systems. Peritoneal tuberculosis represents an uncommon manifestation of extrapulmonary tuberculosis and often presents with vague and nonspecific clinical features, frequently mimicking intra-abdominal malignancies and posing a significant diagnostic challenge. We report the case of a 24-year-old immunocompetent female patient who presented with symptomatic cholelithiasis and underwent elective laparoscopic cholecystectomy. Intraoperatively, multiple whitish, millet-sized nodules were incidentally identified over the peritoneum, liver surface, and omentum. Histopathological examination confirmed caseating granulomatous inflammation consistent with tuberculosis. The patient was subsequently started on anti-tubercular therapy and showed good clinical improvement on follow-up. This case highlights the importance of intraoperative vigilance, the role of laparoscopy, and the necessity of histopathological confirmation in differentiating tuberculosis from malignancy in endemic regions.

Cureus
Good health and well-being
Openalex Percentile: Top 5%
Diagnosis and treatment of tuberculosis
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.