Isolation of a Multidrug-Resistant Candida auris Clade V from an Asymptomatic Acute Myeloid Leukemia Patient in the Intensive Care Unit
Candida auris is a multidrug-resistant fungal pathogen, that rapidly spreads within healthcare settings. Here, a acute myeloid leukemia patient undergoing chemotherapy was admitted to the intensive care unit. From the skin, C. auris was isolated and with whole genome sequencing allocated to clade V. Antifungal susceptibility testing showed azole and echinocandin resistance, with the presence of the ERG11 Y132F mutation, while FKS1 was wild-type. This report presents the first multidrug resistant C. auris clade V isolate.
Authors
- Javad Javidnia (ORCID: https://orcid.org/0000-0001-9336-2518)
- Mahdi Abastabar (ORCID: https://orcid.org/0000-0002-0016-2849)
- Azam Moslemi (ORCID: https://orcid.org/0000-0002-7324-7456)
- Bram Spruijtenburg (ORCID: https://orcid.org/0000-0002-6734-361X)
- Reza Valadan (ORCID: https://orcid.org/0000-0002-9074-6994)
- Zoha Asgari
- Maryam Salimi (ORCID: https://orcid.org/0000-0001-9336-2518)
- Eelco F.J. Meijer (ORCID: https://orcid.org/0000-0002-0226-024X)
- Tahereh Shokohi (ORCID: https://orcid.org/0000-0003-3094-8436)
Institutions
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- Islamic Azad University Sari Branch (IR)
- Canisius-Wilhelmina Ziekenhuis (NL)
- Mazandaran University of Medical Sciences (IR)
Publication Details
- Journal
- Medical Mycology Case Reports
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1016/j.mmcr.2026.100794
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00