Photothermal‐Activated Antibacterial Amyloid‐Polyphenol‐Iron Hydrogels for Synergistic Wound Healing

and the amyloid-polyphenol complex (LT), while hydrogen bonding contributes to network stabilization. This mechanism is amplified at elevated temperatures and under optimized concentrations. Notably, the formed amyloid-polyphenol-iron (LTFe) hydrogel exhibits exceptional photothermal conversion efficiency (88.56%), robust cycling stability, excellent biocompatibility, and potent antibacterial efficacy against both Gram-negative (E. coli) and Gram-positive (S. aureus) bacteria. In vivo studies confirmed that LTFe eradicated pathogens, suppressed inflammatory cytokines, and accelerated wound regeneration. Overall, our work introduces a versatile strategy for designing high-efficiency and high-biocompatibility NIR-responsive hydrogel systems.