Cutaneous Presentation of Pre‐B Cell Acute Lymphoblastic Leukemia in a 3‐Month‐Old Boy

We present a rare case of leukemia cutis as the sole presenting sign of pre-B cell acute lymphoblastic leukemia in a 3-month-old boy. The patient exhibited a solitary, erythematous scalp nodule without systemic symptoms or abnormal peripheral laboratory findings, ultimately diagnosed via biopsy and treated successfully. This case highlights the importance of early dermatologic evaluation and biopsy in persistent or atypical infant scalp lesions.

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Publication Details

Journal
Pediatric Dermatology
Published
2026-05-10
DOI
https://doi.org/10.1111/pde.70242
Primary Topic
Skin Diseases and Diabetes
Type
article
Field-Weighted Citation Impact
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article

Cutaneous Presentation of Pre‐B Cell Acute Lymphoblastic Leukemia in a 3‐Month‐Old Boy

Luke A. Scherz, Erika Tvedten, Robert Duffy, Kim HooKim‐Vickers
Pediatric Dermatology
Skin Diseases and Diabetes
article

Cutaneous Presentation of Pre‐B Cell Acute Lymphoblastic Leukemia in a 3‐Month‐Old Boy

Luke A. Scherz, Erika Tvedten, Robert Duffy, Kim HooKim‐Vickers
article en

Abstract

We present a rare case of leukemia cutis as the sole presenting sign of pre-B cell acute lymphoblastic leukemia in a 3-month-old boy. The patient exhibited a solitary, erythematous scalp nodule without systemic symptoms or abnormal peripheral laboratory findings, ultimately diagnosed via biopsy and treated successfully. This case highlights the importance of early dermatologic evaluation and biopsy in persistent or atypical infant scalp lesions.

Pediatric Dermatology
Cooper University Hospital (US), Cooper Medical School of Rowan University (US), Cooper University Health Care (US)
Openalex Percentile: Top 5%
Skin Diseases and Diabetes
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Cutaneous Presentation of Pre‐B Cell Acute Lymphoblastic Leukemia in a 3‐Month‐Old Boy — Luke A. Scherz, Erika Tvedten, et al. · Pediatric Dermatology (2026) | TGRS Research Map | TGRS