Formulation And Development of Polyherbal Effervescent Granules for The Treatment of Inflammatory Bowel Disease

Inflammatory Bowel Disease (IBD) is a chronic inflammatory disorder affecting the gastrointestinal tract, primarily including Crohn’s disease and Ulcerative colitis. The present study aims to formulate and evaluate polyherbal effervescent granules using extracts of Bauhinia variegata and Clitoria ternatea. These plants possess significant anti-inflammatory, antioxidant, and immunomodulatory properties. Effervescent granules were prepared using the wet granulation method and evaluated for physicochemical parameters such as flow properties, effervescence time, pH, and stability. The results indicated that the formulation exhibited good flow properties, rapid effervescence, and acceptable stability. The study concludes that the developed formulation may serve as a promising herbal alternative for managing IBD.