A Giant Fibroepithelial Polyp of the Nipple: A Case Report of a Rare Benign Tumor

Fibroepithelial polyps (FEPs) are rare benign tumors that most commonly arise in the lower female genital tract, including the vagina, vulva, and cervix. Occurring in the breast, particularly the nipple, is extremely rare and may clinically and radiologically mimic malignant disease. A woman in her early 50s presented to the breast one-stop clinic with a progressively enlarging pedunculated lesion arising from the nipple. She reported a longstanding small nipple tag since childhood that had recently increased significantly in size. Clinical examination revealed a 9 x 7 cm soft, exophytic, pedunculated mass arising from the nipple. Breast imaging showed no underlying abnormality. The patient underwent day-case surgical excision under general anesthesia with preservation of the nipple and uncomplicated recovery. The specimen weighed 130 g. Histopathology demonstrated a fibrovascular lesion with dense collagenous stroma and overlying hyperplastic epithelium, without atypia or malignancy. FEP of the nipple is an exceptionally rare entity that should be considered in the differential diagnosis of nipple lesions. Surgical excision is curative and allows excellent cosmetic and functional outcomes.

Authors

Publication Details

Journal
Cureus
Published
2026-05-09
DOI
https://doi.org/10.7759/cureus.108537
Primary Topic
Urologic and reproductive health conditions
Type
article
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article

A Giant Fibroepithelial Polyp of the Nipple: A Case Report of a Rare Benign Tumor

Jaideep Rait, Saif S Al Sahee, Layloma Hamidi-Latifi
Cureus
Urologic and reproductive health conditions
article

A Giant Fibroepithelial Polyp of the Nipple: A Case Report of a Rare Benign Tumor

Jaideep Rait, Saif S Al Sahee, Layloma Hamidi-Latifi
article en

Abstract

Fibroepithelial polyps (FEPs) are rare benign tumors that most commonly arise in the lower female genital tract, including the vagina, vulva, and cervix. Occurring in the breast, particularly the nipple, is extremely rare and may clinically and radiologically mimic malignant disease. A woman in her early 50s presented to the breast one-stop clinic with a progressively enlarging pedunculated lesion arising from the nipple. She reported a longstanding small nipple tag since childhood that had recently increased significantly in size. Clinical examination revealed a 9 x 7 cm soft, exophytic, pedunculated mass arising from the nipple. Breast imaging showed no underlying abnormality. The patient underwent day-case surgical excision under general anesthesia with preservation of the nipple and uncomplicated recovery. The specimen weighed 130 g. Histopathology demonstrated a fibrovascular lesion with dense collagenous stroma and overlying hyperplastic epithelium, without atypia or malignancy. FEP of the nipple is an exceptionally rare entity that should be considered in the differential diagnosis of nipple lesions. Surgical excision is curative and allows excellent cosmetic and functional outcomes.

Cureus
Openalex Percentile: Top 6%
Urologic and reproductive health conditions
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A Giant Fibroepithelial Polyp of the Nipple: A Case Report of a Rare Benign Tumor — Jaideep Rait, Saif S Al Sahee, et al. · Cureus (2026) | TGRS Research Map | TGRS