Presumed Idiopathic Replacement Resorption in a Permanent First Molar in a Child With Multiple Tooth Agenesis: A Case Report

Replacement resorption is a rare pathological condition in permanent teeth, characterized by progressive substitution of root dentin with bone tissue, typically following traumatic injuries. This case report presents an unusual occurrence of replacement resorption in the mesial root of the mandibular right first permanent molar (46) in an eight-year-old boy with no documented history of trauma, associated with non-syndromic agenesis of multiple permanent teeth (15, 34, 35, 44, 45). Despite the reserved long-term prognosis, conservative endodontic management was pursued due to the significant tooth agenesis. This case highlights the importance of advanced imaging in diagnosis, the challenges of managing replacement resorption, and the potential for successful conservative treatment when appropriate protocols are followed.

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Publication Details

Journal
Cureus
Published
2026-05-09
DOI
https://doi.org/10.7759/cureus.108533
Primary Topic
dental development and anomalies
Type
article
Field-Weighted Citation Impact
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article

Presumed Idiopathic Replacement Resorption in a Permanent First Molar in a Child With Multiple Tooth Agenesis: A Case Report

Cristina Coralia Nistor, Anca Oana Dragomirescu, Ioana Suciu
Cureus
dental development and anomalies
article

Presumed Idiopathic Replacement Resorption in a Permanent First Molar in a Child With Multiple Tooth Agenesis: A Case Report

Cristina Coralia Nistor, Anca Oana Dragomirescu, Ioana Suciu
article en

Abstract

Replacement resorption is a rare pathological condition in permanent teeth, characterized by progressive substitution of root dentin with bone tissue, typically following traumatic injuries. This case report presents an unusual occurrence of replacement resorption in the mesial root of the mandibular right first permanent molar (46) in an eight-year-old boy with no documented history of trauma, associated with non-syndromic agenesis of multiple permanent teeth (15, 34, 35, 44, 45). Despite the reserved long-term prognosis, conservative endodontic management was pursued due to the significant tooth agenesis. This case highlights the importance of advanced imaging in diagnosis, the challenges of managing replacement resorption, and the potential for successful conservative treatment when appropriate protocols are followed.

Cureus
Good health and well-being
Openalex Percentile: Top 8%
dental development and anomalies
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Presumed Idiopathic Replacement Resorption in a Permanent First Molar in a Child With Multiple Tooth Agenesis: A Case Report — Cristina Coralia Nistor, Anca Oana Dragomirescu, et al. · Cureus (2026) | TGRS Research Map | TGRS