Infectious complications of ANCA-associated vasculitis: Description and associated outcome
INTRODUCTION: In ANCA-associated vasculitis (AAV), both the disease and its treatments contribute to systemic complications, among which, infections represent a major cause of morbidity and mortality. This study aimed to evaluate the prevalence and prognosis of infectious complications in AAV, to identify associated risk factors, and to describe long-term outcomes. METHODS: , 2025. RESULTS: [1.59-2.91], p<0.001). CONCLUSION: Infections are frequent complications in AAV, and exert an independent impact on mortality. Anti-PR3 positivity increases infection risk, whereas methotrexate appears protective.
Authors
- Julia Torrents
- F. A. LeFEVRE (ORCID: https://orcid.org/0009-0000-7212-190X)
- P L Brunet
- Justine Solignac (ORCID: https://orcid.org/0000-0002-3621-3329)
- Gilles Kaplanski (ORCID: https://orcid.org/0000-0002-0892-9207)
- Jeanne Morin
- Stéphane Burtey (ORCID: https://orcid.org/0000-0003-1813-7884)
- Julien Faraut
- Laurent Daniel (ORCID: https://orcid.org/0000-0002-7539-0109)
- Mickaël Bobot (ORCID: https://orcid.org/0000-0002-9451-0372)
- Pierre-André Jarrot
- Noémie Jourde-Chiche
Institutions
- Inserm (FR)
- Aix-Marseille Université (FR)
- Assistance Publique Hôpitaux de Marseille (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Hôpital de la Conception (FR)
- Hôpital de la Timone (FR)
Publication Details
- Journal
- European Journal of Internal Medicine
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1016/j.ejim.2026.106931
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00