Clinical Outcomes of High-Dose Ampicillin-Sulbactam Combined with Colistin in the Treatment of Ventilator-Associated Pneumonia Caused by Carbapenem-Resistant <i>Acinetobacter baumannii</i>.

< 0.001). High-dose ampicillin-sulbactam combined with colistin significantly improves microbiological clearance and survival in patients with CRAB-VAP. Despite a higher incidence of transient nephrotoxicity, the regimen provides a substantial survival benefit.

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Publication Details

Journal
PubMed
Published
2026-05-08
DOI
https://doi.org/10.1177/10766294261448634
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
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article

Clinical Outcomes of High-Dose Ampicillin-Sulbactam Combined with Colistin in the Treatment of Ventilator-Associated Pneumonia Caused by Carbapenem-Resistant Acinetobacter baumannii.

Thi Huong Bui, Tiep Khac Nguyen, Thanh Tat Nguyen, Bui Hai Hoang et al.
PubMed
Antibiotic Resistance in Bacteria
article

Clinical Outcomes of High-Dose Ampicillin-Sulbactam Combined with Colistin in the Treatment of Ventilator-Associated Pneumonia Caused by Carbapenem-Resistant Acinetobacter baumannii.

Thi Huong Bui, Tiep Khac Nguyen, Thanh Tat Nguyen, Bui Hai Hoang, Son Thai Dinh, Linh Khanh Nguyen
article en

Abstract

< 0.001). High-dose ampicillin-sulbactam combined with colistin significantly improves microbiological clearance and survival in patients with CRAB-VAP. Despite a higher incidence of transient nephrotoxicity, the regimen provides a substantial survival benefit.

PubMed
Hanoi Medical University (VN), Hanoi University of Pharmacy (VN), Viet Duc Hospital (VN), Hanoi Medical University Hospital (VN)
Good health and well-being
Openalex Percentile: Top 10%
Antibiotic Resistance in Bacteria
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