Diffusion weighted imaging-based tumor growth rate for predicting long-term survival in nasopharyngeal carcinoma
BACKGROUND: To explore the prognostic value of tumor special growth rate (TSGR) in patients with NPC and investigate the potential of diffusion-weighted imaging (DWI) habitat analysis as a surrogate marker. METHODS: /s]) of each subregion was calculated. ADC values for diagnosing TSGR and predicting survival were evaluated and validated using 5-fold cross-validation (iterations = 1000) and in an independent cohort. RESULTS: further improved the predictive value of TNM stage (0.663-0.848 vs. 0.631-0.785). CONCLUSION: value may have the rapid-growth potential and were more likely to have a poor prognosis.
Authors
- Yu Zhao (ORCID: https://orcid.org/0000-0003-1874-908X)
- Xiaoduo Yu (ORCID: https://orcid.org/0000-0002-0893-695X)
- Sai Wang
- F Yang
- Meng Lin
- Xiaolu Li
- Hongmei Zhang
- Haoran Wei
- Lizhi Xie
- Michael Iv
- Lin Li
- Dehong Luo
- Ya Zhang
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Cancer Center (US)
- Stanford University (US)
Publication Details
- Journal
- Cancer Imaging
- Published
- 2026-05-09
- DOI
- https://doi.org/10.1186/s40644-026-01041-9
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00