Three cryo-EM structures of complement C3d-bound α<sub>M</sub>β<sub>2</sub> reveal an unexpected layer of dynamics for αI-containing integrin receptors.

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PubMed
Published
2026-05-08
DOI
https://doi.org/10.1126/sciadv.aea7241
Primary Topic
Cell Adhesion Molecules Research
Type
article
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article

Three cryo-EM structures of complement C3d-bound αMβ2 reveal an unexpected layer of dynamics for αI-containing integrin receptors.

Martin Høgholm Jørgensen, Rasmus Kock Flygaard, Rasmus K. Jensen, Marlene Uglebjerg Fruergaard et al.
PubMed
Cell Adhesion Molecules Research
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Three cryo-EM structures of complement C3d-bound αMβ2 reveal an unexpected layer of dynamics for αI-containing integrin receptors.

Martin Høgholm Jørgensen, Rasmus Kock Flygaard, Rasmus K. Jensen, Marlene Uglebjerg Fruergaard, Zsuzsa Bajtay, Daan Vorselen, Simon A. Mortensen, Josefine Lorentzen, Václav Hořejšı́, Gregers Rom Andersen, Szilvia Lukácsi, Timo Lambertus Gerardus van Veghel, Krzysztof Jakub Pietrzak-Lichwa
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Abstract

No abstract available for this paper.
PubMedVol. 12(19)
Eötvös Loránd University (HU), Aarhus University (DK), Czech Academy of Sciences, Institute of Molecular Genetics (CZ), European Molecular Biology Laboratory (DE), Wageningen University & Research (NL)
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Cell Adhesion Molecules Research
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