The genetic landscape of antibiotic sensitivity in <i>Staphylococcus aureus</i>.
. Our detailed profiling of drug-gene, gene-gene, and drug-drug interactions reveals important functional relationships among essential genes and defines a vulnerability landscape to guide drug target discovery and effective combination therapies.
Authors
- Saeed Tavazoie (ORCID: https://orcid.org/0000-0003-2183-4162)
- Menghan Liu (ORCID: https://orcid.org/0000-0002-9390-8194)
- Panos Oikonomou (ORCID: https://orcid.org/0000-0001-7387-0312)
- Li Wan (ORCID: https://orcid.org/0000-0002-9797-0315)
- Wenyan Jiang (ORCID: https://orcid.org/0000-0002-0593-0296)
- Julia Hettleman
- Joseph Gonzalez
- Sydney Blattman
- Qiaoyu Hu
- Howe Chen (ORCID: https://orcid.org/0009-0007-3579-4268)
- Mirela Berisa
- Falguni Paul
Institutions
- Columbia University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- PubMed
- Published
- 2026-05-08
- DOI
- https://doi.org/10.1126/sciadv.aeb9875
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00