Impact of Clinical Pharmacist on Drug-Related Problems in Pediatric Patients with Nephrotic Syndrome

Background: Nephrotic Syndrome (NS) is a common pediatric renal ailment in India. Steroids and immunosuppressants are utilized to treat the condition, which has side effects for the patients. One of the fundamental principles of pharmacological treatment is the assessment, diagnosis, prevention, and resolution of Drug-Related Problems (DRPs). Objective: To identify and characterize Drug-Related Problems in pediatric patients with nephrotic syndrome. Materials & Methods: Patients with nephrotic syndrome, with or without co-morbidities, were the subjects of this prospective interventional trial, which was carried out at the pediatric nephrology department of a tertiary care teaching hospital. 88 patients from both the inpatient and outpatient departments, ranging in age from 4 to 18, participated in the study. The study excluded individuals with cancer and those who did not provide their consent. Along with usual care, the patients received a Patient Information Leaflet (PIL) and patient counseling. Intervention was used to identify and address the causes and issues related to drug-related problems. Results: Among 88 recruited patients, 56 (64%) were male and 32 (36%) were female. According to the data, it was confirmed that the male population has a higher prevalence than the female population. Out of 88 recruited patients, Drug-Related Problems (DRPs) were found in 52 (59.09%) patients, and DRPs were absent in 36 (40.91%) patients. Drug-Related Problems (DRPs) were solved by providing pharmacist intervention. Conclusion: Clinical pharmacists are needed to provide the knowledge and counselling to the patient for the betterment of their lives.