Carbon Monoxide Poisoning, Gas Embolism and Fluid overload During Resectoscopic Myomectomy

Resectoscopic myomectomy (RM) is a standard minimally invasive procedure but carries risks of distinct complications. We report a rare case of a 36-year-old woman who simultaneously developed a triad of life-threatening complications during HM: carbon monoxide poisoning, gas embolism, and fluid overload. The patient presented with precipitous drops in end-tidal carbon dioxide and bispectral index silence. Arterial blood gas analysis revealed severe metabolic acidosis, electrolyte disturbances, and a carboxyhemoglobin level of 27.1%. Definitive diagnosis via arterial blood gas analysis and subsequent multimodal management, bolstered by the patient’s excellent physiological reserve, led to a full recovery. This case highlights the critical need for strict fluid management during RM and CO-oximetry's indispensable role in detecting concurrent carbon monoxide toxicity.

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Publication Details

Journal
AJOG Global Reports
Published
2026-05-01
DOI
https://doi.org/10.1016/j.xagr.2026.100644
Primary Topic
Heme Oxygenase-1 and Carbon Monoxide
Type
article
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article

Carbon Monoxide Poisoning, Gas Embolism and Fluid overload During Resectoscopic Myomectomy

苏咸, Yuting Li, Zhen-Zhen Xu, Xue Li et al.
AJOG Global Reports
Heme Oxygenase-1 and Carbon Monoxide
article

Carbon Monoxide Poisoning, Gas Embolism and Fluid overload During Resectoscopic Myomectomy

苏咸, Yuting Li, Zhen-Zhen Xu, Xue Li, Ye Lu, Lei Zhang, Ying Liang, Ting Ding
article en

Abstract

Resectoscopic myomectomy (RM) is a standard minimally invasive procedure but carries risks of distinct complications. We report a rare case of a 36-year-old woman who simultaneously developed a triad of life-threatening complications during HM: carbon monoxide poisoning, gas embolism, and fluid overload. The patient presented with precipitous drops in end-tidal carbon dioxide and bispectral index silence. Arterial blood gas analysis revealed severe metabolic acidosis, electrolyte disturbances, and a carboxyhemoglobin level of 27.1%. Definitive diagnosis via arterial blood gas analysis and subsequent multimodal management, bolstered by the patient’s excellent physiological reserve, led to a full recovery. This case highlights the critical need for strict fluid management during RM and CO-oximetry's indispensable role in detecting concurrent carbon monoxide toxicity.

AJOG Global Reports
Peking University (CN), Peking University First Hospital (CN)
Clean water and sanitation
Openalex Percentile: Top 8%
Heme Oxygenase-1 and Carbon Monoxide
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