Design, synthesis, and molecular docking evaluation of novel pyrimidine–thiadiazole glycosides as potential anticancer agents
is the most promising candidate in this series, with both enhanced cytotoxic activity and favorable docking interactions, suggesting that pyrimidine-thiadiazole hybrids represent a valuable scaffold for further anticancer drug development.
Authors
- Ahmed F. El‐Farargy (ORCID: https://orcid.org/0000-0001-7636-0860)
- Wassila Derafa
- Eiman A.A Elshaygi
- Abdullah Y. Abdullah Alzahrani
- Amira A. Ghoneim
Institutions
- Zagazig University (EG)
- Jouf University (SA)
- Najran University (SA)
- King Khalid University (SA)
Publication Details
- Journal
- Nucleosides Nucleotides & Nucleic Acids
- Published
- 2026-05-09
- DOI
- https://doi.org/10.1080/15257770.2026.2664609
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.00