Left-Sided Sciatic Nerve Endometriosis Presenting As Chronic Thigh Pain and Muscle Atrophy: A Case Report

Sciatic nerve endometriosis is a rare and often underdiagnosed form of deep infiltrating endometriosis involving the lumbosacral plexus or sciatic nerve. We present the case of a 40-year-old woman with chronic left thigh and pelvic pain exacerbated during menstruation, accompanied by limited mobility. Pelvic MRI revealed a lesion along the left sciatic nerve with characteristic hemorrhagic and inflammatory features, as well as muscle atrophy indicative of chronic denervation. Combined surgical and gynecologic intervention confirmed the diagnosis and resulted in significant symptom improvement. This case highlights the importance of clinical suspicion and MRI in early diagnosis to prevent irreversible neurologic damage.

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Publication Details

Journal
Cureus
Published
2026-05-09
DOI
https://doi.org/10.7759/cureus.108539
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
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article

Left-Sided Sciatic Nerve Endometriosis Presenting As Chronic Thigh Pain and Muscle Atrophy: A Case Report

Akbar Hajiyev, Parviz Samadov, Emil Hasanov, Ilhama Eldarova et al.
Cureus
Endometriosis Research and Treatment
article

Left-Sided Sciatic Nerve Endometriosis Presenting As Chronic Thigh Pain and Muscle Atrophy: A Case Report

Akbar Hajiyev, Parviz Samadov, Emil Hasanov, Ilhama Eldarova, Kamil Aliyev
article en

Abstract

Sciatic nerve endometriosis is a rare and often underdiagnosed form of deep infiltrating endometriosis involving the lumbosacral plexus or sciatic nerve. We present the case of a 40-year-old woman with chronic left thigh and pelvic pain exacerbated during menstruation, accompanied by limited mobility. Pelvic MRI revealed a lesion along the left sciatic nerve with characteristic hemorrhagic and inflammatory features, as well as muscle atrophy indicative of chronic denervation. Combined surgical and gynecologic intervention confirmed the diagnosis and resulted in significant symptom improvement. This case highlights the importance of clinical suspicion and MRI in early diagnosis to prevent irreversible neurologic damage.

Cureus
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Endometriosis Research and Treatment
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