Fibroids and infertility

The presence of uterine fibroids impacts fertility through multiple mechanisms. While subserosal fibroids have minimal impact, especially when of reduced size, the presence of intramural fibroids impacts both the likelihood of pregnancy and its outcomes. Submucosal fibroids significantly reduce the chance of pregnancy and increase pregnancy complications. While noninvasive techniques can treat fibroids and appear safe, surgical management of FIGO Type 0, 1, 2, and 3 fibroids remains the gold standard in women desiring pregnancy. Uterine artery embolization is not recommended. Where the ovaries are not visible due to the presence of large fibroids, assisted reproduction and transvaginal oocyte pick-up become a challenge and consideration for myomectomy should be given. A cesarean section should be performed for women where the uterine cavity has been opened at the time of myomectomy.

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Publication Details

Journal
International Journal of Gynecology & Obstetrics
Published
2026-05-09
DOI
https://doi.org/10.1002/ijgo.71062
Primary Topic
Uterine Myomas and Treatments
Type
article
Field-Weighted Citation Impact
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article

Fibroids and infertility

Dov Feldberg, Christina O'Brien, Ivonne Díaz, Edgar Mocanu et al.
International Journal of Gynecology & Obstetrics
Uterine Myomas and Treatments
article

Fibroids and infertility

Dov Feldberg, Christina O'Brien, Ivonne Díaz, Edgar Mocanu, Nikhil Purandare, Basil Tarlatzis
article en

Abstract

The presence of uterine fibroids impacts fertility through multiple mechanisms. While subserosal fibroids have minimal impact, especially when of reduced size, the presence of intramural fibroids impacts both the likelihood of pregnancy and its outcomes. Submucosal fibroids significantly reduce the chance of pregnancy and increase pregnancy complications. While noninvasive techniques can treat fibroids and appear safe, surgical management of FIGO Type 0, 1, 2, and 3 fibroids remains the gold standard in women desiring pregnancy. Uterine artery embolization is not recommended. Where the ovaries are not visible due to the presence of large fibroids, assisted reproduction and transvaginal oocyte pick-up become a challenge and consideration for myomectomy should be given. A cesarean section should be performed for women where the uterine cavity has been opened at the time of myomectomy.

International Journal of Gynecology & Obstetrics
Royal College of Surgeons in Ireland (IE), Aristotle University of Thessaloniki (GR), Rotunda Hospital (IE), Rabin Medical Center (IL), University Hospital Galway (IE), Military University Nueva Granada (CO), Fundación Universitaria Sanitas (CO)
Good health and well-being
Openalex Percentile: Top 5%
Uterine Myomas and Treatments
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