Offline Two-Stage SEC and LC-MS/MS for Comprehensive Characterization of Yeast Ribosomal Populations
knockout, we show that 2D-SEC MS/MS detects rapid polysome collapse and changes to the polysome profiling ratios, illustrating its capacity to link ribosome composition to functional perturbations.
Authors
- Joshua J. Hamey (ORCID: https://orcid.org/0000-0002-0463-8955)
- Marc Wilkins
- Andrew J. Spiteri (ORCID: https://orcid.org/0009-0003-7898-9824)
Institutions
- UNSW Sydney (AU)
- Biotechnology Research Center (IR)
Publication Details
- Journal
- Journal of Proteome Research
- Published
- 2026-05-08
- DOI
- https://doi.org/10.1021/acs.jproteome.5c00945
- Primary Topic
- RNA and protein synthesis mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Australian Research Council