Real-world data on the impact of dose reduction measures on radiation exposure in CT perfusion of the brain
Large real-world cohort evaluating dose optimization measures in brain CT perfusion. Reduced tube current and longer sampling intervals lowered dose by up to 67.7%. Optimized protocols achieved radiation levels comparable to non-contrast head CT. Dose reduction translated into substantial decreases in estimated lifetime cancer risk. Benefits were most pronounced in younger patients undergoing CT perfusion imaging.
Authors
- Thomas Stein (ORCID: https://orcid.org/0009-0002-3277-269X)
- Till Schürmann (ORCID: https://orcid.org/0009-0004-4230-7681)
- Martin Fiebich (ORCID: https://orcid.org/0000-0001-6596-8774)
- Friederike Lang (ORCID: https://orcid.org/0000-0002-2327-1044)
- Alexander Rau (ORCID: https://orcid.org/0000-0001-5881-6043)
- F Bamberg
- Elias Kellner
- Horst Urbach
Institutions
- University of Freiburg (DE)
- University Medical Center Freiburg (DE)
- Technische Hochschule Mittelhessen (DE)
Publication Details
- Journal
- European Journal of Radiology Open
- Published
- 2026-05-08
- DOI
- https://doi.org/10.1016/j.ejro.2026.100759
- Primary Topic
- Radiation Dose and Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Albert-Ludwigs-Universität Freiburg
- Medizinische Fakultät der Albert-Ludwigs-Universität Freiburg