Akkermansia muciniphila drives viscero-visceral crosstalk via 5-HT3aR-mediated sensitization of dichotomizing gut–bladder neurons

Authors

Wanfu Li (ORCID: https://orcid.org/0009-0005-9665-8206)
Wentai Shangguan (ORCID: https://orcid.org/0000-0001-8103-9078)
Ming Xie
Xinhang Shi (ORCID: https://orcid.org/0000-0001-6298-527X)
Li Li (ORCID: https://orcid.org/0009-0003-4636-9487)
Yuexuan Zhu
Zongwei Wang (ORCID: https://orcid.org/0000-0002-1215-2912)
Gao Y
Bisheng Cheng (ORCID: https://orcid.org/0009-0005-2300-3583)
Zhangrui Zhu
Qishen Yang
Rulin Liao
Yao Yu
Jie Zhao (ORCID: https://orcid.org/0000-0002-7751-4435)
Jun Zheng
Jiao Zeng
Peng Wu (ORCID: https://orcid.org/0000-0003-2026-4102)
Haotian Jiang
Qi Sun

Institutions

Beth Israel Deaconess Medical Center (US)
Harvard University (US)
Guangdong Pharmaceutical University (CN)
Ministry of Education (RW)
Nanfang Hospital (CN)
University of Hong Kong - Shenzhen Hospital (CN)
Southern Medical University (CN)
University of Hong Kong (HK)

Publication Details

Journal: Experimental & Molecular Medicine
Published: 2026-05-08
DOI: https://doi.org/10.1038/s12276-026-01720-4
Primary Topic: Gastrointestinal motility and disorders
Type: article
Field-Weighted Citation Impact: 0.00

Funders

National Natural Science Foundation of China
China Postdoctoral Science Foundation
Basic and Applied Basic Research Foundation of Guangdong Province

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article

Akkermansia muciniphila drives viscero-visceral crosstalk via 5-HT3aR-mediated sensitization of dichotomizing gut–bladder neurons

Wanfu Li, Wentai Shangguan, Ming Xie, Xinhang Shi et al.

May 8, 2026

Experimental & Molecular Medicine

Gastrointestinal motility and disorders

article

Akkermansia muciniphila drives viscero-visceral crosstalk via 5-HT3aR-mediated sensitization of dichotomizing gut–bladder neurons

Wanfu Li, Wentai Shangguan, Ming Xie, Xinhang Shi, Li Li, Yuexuan Zhu, Zongwei Wang, Gao Y, Bisheng Cheng, Zhangrui Zhu, Qishen Yang, Rulin Liao, Yao Yu, Jie Zhao, Jun Zheng, Jiao Zeng, Peng Wu, Haotian Jiang, Qi Sun

May 8, 2026article en

Abstract

No abstract available for this paper.

Experimental & Molecular Medicine

Beth Israel Deaconess Medical Center (US), Harvard University (US), Guangdong Pharmaceutical University (CN), Ministry of Education (RW), Nanfang Hospital (CN), University of Hong Kong - Shenzhen Hospital (CN), Southern Medical University (CN), University of Hong Kong (HK)

National Natural Science Foundation of China, China Postdoctoral Science Foundation, Basic and Applied Basic Research Foundation of Guangdong Province

Openalex Percentile: Top 4%

Gastrointestinal motility and disorders

DOI Open Access PDF OpenAlex

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Akkermansia muciniphila drives viscero-visceral crosstalk via 5-HT3aR-mediated sensitization of dichotomizing gut–bladder neurons — Wanfu Li, Wentai Shangguan, et al. · Experimental & Molecular Medicine (2026) | TGRS Research Map | TGRS