Synthesis and Reactivity of 3‐Aminosydnones in Cycloaddition Reactions With Alkynes
We present in this article the synthesis, functionalization, and properties of 3-aminosydnones, a forgotten class of mesoionic compounds. Their capacity to react as 1,3-dipoles in cycloaddition reactions with cyclic alkynes was investigated, revealing their potential as valuable tools for bioconjugation applications.
Authors
- Davide Audisio (ORCID: https://orcid.org/0000-0002-6234-3610)
- David‐Alexandre Buisson
- Alexis Leblais
- Frédéric Taran (ORCID: https://orcid.org/0000-0001-5461-329X)
- Timothée D’Anfray
- Guillaume Force
- Maxime Tricoire (ORCID: https://orcid.org/0000-0002-7190-669X)
- Apolline Dominic
Institutions
- Centre National de la Recherche Scientifique (FR)
- Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR)
- Université Paris-Saclay (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- CEA Paris-Saclay (FR)
Publication Details
- Journal
- Chemistry - A European Journal
- Published
- 2026-05-08
- DOI
- https://doi.org/10.1002/chem.71110
- Primary Topic
- Synthesis and Characterization of Pyrroles
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- California Earthquake Authority
- Agence Nationale de la Recherche