Polyurethane-based targeted active nanocarriers for colon cancer treatment
release studies indicated sustained drug delivery over 19 days. Flow cytometry analysis revealed that CUR-loaded nanoparticles reduced HT-29 cell viability to 66.35%, and FO conjugation further decreased it to 52.74%. The FO-CUR-TPU-OLE-PEG nanoparticle system exhibits strong potential as a targeted therapeutic platform for colon cancer and represents a promising alternative to currently available formulations.
Authors
- Zeynep Karahaliloğlu (ORCID: https://orcid.org/0000-0001-6711-9792)
- Baki Hazer
- Gamze Usta
Institutions
- Aksaray University (TR)
- Zonguldak Bülent Ecevit University (TR)
Publication Details
- Journal
- Journal of Microencapsulation
- Published
- 2026-05-08
- DOI
- https://doi.org/10.1080/02652048.2026.2667730
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Aksaray Üniversitesi
- Kapadokya Üniversitesi