Correspondence on: “Bioinformatics and network pharmacology-based investigation of matrine’s therapeutic roles in breast cancer”

This commentary reviews a study by Qu et al. on the potential mechanisms of matrine in breast cancer using bioinformatics and network pharmacology. While commending the systematic approach, the commentary highlights the limitations of small dataset size, the need for experimental validation, and the importance of pharmacokinetic considerations. Future studies integrating molecular dynamics and in vivo models are recommended to enhance translational potential.