Cooperative Sulfate Binding Drives Hierarchical Assembly of Supramolecular Trimers
electrostatic attraction. The trimer remains stable in solution, as confirmed by NMR, DOSY, and ESI-MS experiments. Concentration-dependent NMR studies elucidate a multistep assembly pathway from a 1:1 sulfate complex, through a figure-eight subunit, to the final architecture. Moreover, replacing the non-coordinating pyridine unit with a chiral group successfully induces enantiopure trimers. This work establishes a paradigm of anion-dictated assembly through cooperative first- and second-sphere coordination, offering a new avenue for supramolecular assemblies.
Authors
- Kanglei Liu
- Weidong Zhao (ORCID: https://orcid.org/0000-0002-4444-6595)
- N Li (ORCID: https://orcid.org/0000-0001-6800-7389)
- Le Dai
- Yi-Xiang Wang (ORCID: https://orcid.org/0000-0002-5246-5497)
- Li Yan
- Zhiwen Sun
- Cheng Jin
- Biao Wu (ORCID: https://orcid.org/0000-0002-0724-4150)
- Heng Wang (ORCID: https://orcid.org/0000-0002-6829-7205)
- Fang Fang
Institutions
- Beijing Institute of Technology (CN)
- Analysis and Testing Centre (CN)
- Shanghai Institute of Organic Chemistry (CN)
- Beijing Academy of Science and Technology (CN)
- Ministry of Industry and Information Technology (CN)
Publication Details
- Journal
- Angewandte Chemie International Edition
- Published
- 2026-05-08
- DOI
- https://doi.org/10.1002/anie.1058616
- Primary Topic
- Supramolecular Chemistry and Complexes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Beijing Municipality