Oxygen–Oxygen Bond-Forming Reactions for the Synthesis of Cyclic Peroxides

O-labeling experiments and by the determination that the reaction proceeds with retention of configuration at the carbon atoms of the ring. The reaction was rapid at -78 °C, it was high-yielding, and it was general for a range of substrates, including the formation of five- and six-membered cyclic and bicyclic peroxides. This reaction, therefore, serves as a synthetic analogy to the oxygen-oxygen bond formation reaction used in nature to form dioxygen.