Elesestriterpenoid A, an Unprecedented 5/7/6/6/5 Carbon Skeleton with Neuroprotective Activity from Leaves of <i>Eleutherococcus sessiliflorus</i>
demonstrated pronounced efficacy in mitigating oxidative damage through modulation of the Keap1/Nrf2/HO-1 signaling pathway in HT22 cells, indicating its potential for treating nerve injuries.
Authors
- Leixin Zhuang
- J H Wu
- Y Liu
- K Chen (ORCID: https://orcid.org/0000-0001-8103-0065)
- Li Zhang (ORCID: https://orcid.org/0000-0001-8142-403X)
- Yanying Li (ORCID: https://orcid.org/0000-0001-5580-5111)
- Qingshan Chen (ORCID: https://orcid.org/0009-0004-1655-2210)
- S C Zhang
- Meng-Meng Li (ORCID: https://orcid.org/0009-0003-7398-7491)
- Wei Guan
- Juan Pan
- Rui Yang
- Yi-Qiang Zhang
- Dong Han
- Hai-Xue Kuang (ORCID: https://orcid.org/0000-0003-0535-2761)
Institutions
- Northeast Agricultural University (CN)
- Heilongjiang University of Chinese Medicine (CN)
- First Affiliated Hospital of Heilongjiang University of Chinese Medicine (CN)
- Buchang Pharma (China) (CN)
- Beihang University (CN)
Publication Details
- Journal
- Journal of Natural Products
- Published
- 2026-05-08
- DOI
- https://doi.org/10.1021/acs.jnatprod.6c00058
- Primary Topic
- Bioactive Natural Diterpenoids Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00