Emergence of Ceftriaxone-Resistant <i>Neisseria gonorrhoeae penA</i> -60–Carrying Strains, Thailand, 2025

We report 5 gonorrhea cases caused by ceftriaxone-resistant penA-60-carrying Neisseria gonorrhoeae bacteria during January-April 2025 in Thailand, successfully cured by ceftriaxone therapy. Most patients had prior over-the-counter antimicrobial drug exposure. Ceftriaxone-resistant gonococcal strains are spreading in Thailand, and strengthened gonorrhea and resistance surveillance and effective antimicrobial stewardship programs are needed.

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Publication Details

Journal
Emerging infectious diseases
Published
2026-05-08
DOI
https://doi.org/10.3201/eid3206.251860
Primary Topic
Reproductive tract infections research
Type
article
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Emergence of Ceftriaxone-Resistant Neisseria gonorrhoeae penA -60–Carrying Strains, Thailand, 2025

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Emergence of Ceftriaxone-Resistant Neisseria gonorrhoeae penA -60–Carrying Strains, Thailand, 2025

Natnaree Girdthep, Pongsathorn Sangprasert, Rossaphorn Kittiyaowamarn, Ismael Maatouk, Thanakorn Arunngamwong, Sirintra Pharanut, Magnus Unemo, Tawan Nongpian, Ruechakorn Kunkhajornphan
article en

Abstract

We report 5 gonorrhea cases caused by ceftriaxone-resistant penA-60-carrying Neisseria gonorrhoeae bacteria during January-April 2025 in Thailand, successfully cured by ceftriaxone therapy. Most patients had prior over-the-counter antimicrobial drug exposure. Ceftriaxone-resistant gonococcal strains are spreading in Thailand, and strengthened gonorrhea and resistance surveillance and effective antimicrobial stewardship programs are needed.

Emerging infectious diseasesVol. 32(6)
Openalex Percentile: Top 7%
Reproductive tract infections research
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