Women's Knees Are Not Gender‐Neutral: A Global Scoping Review of Equity, Representation, and Context in Knee Osteoarthritis Research and Evidence
= 29.4, p < 0.001). Sex-disaggregated analyses were reported in 38% of mixed-sex studies, with profound neglect of psychosocial, preventive, and mechanistic outcomes. Intersectional analyses combining age, socioeconomic status, and context were extremely rare. Weighted gap scores highlighted very high deficiencies in SES, education, occupation, and LMIC representation, with minimal improvement over 24 years. KOA's evidence base does not merely underrepresent women; it systematically fails to generate clinically validated knowledge for them. As a result, interventions are routinely applied without clear evidence of the effectiveness across the population most affected, without mandatory sex-aggregated, mechanistic, and context-specific research.
Authors
- Emmanuel Okon Enang
- Ezra Onyedikachi Madu
- Minha Awan
Institutions
- Enugu State University of Science and Technology (NG)
- Bahawal Victoria Hospital (PK)
- University of Calabar (NG)
Publication Details
- Journal
- International Journal of Rheumatic Diseases
- Published
- 2026-05-01
- DOI
- https://doi.org/10.1111/1756-185x.70657
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00