Safety evaluation of an extension of use of the food enzyme α‐amylase from the genetically modified Bacillus licheniformis strain NZYM‐BC

strain NZYM-BC by Novozymes A/S. The safety of this food enzyme was evaluated previously and it did not give rise to safety concerns when used in six food manufacturing processes. Subsequently, the applicant has requested to extend its use to include two additional processes and to extend, for one intended use, the range of raw materials to which the food enzyme may be added. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of eight food manufacturing processes. As the food enzyme-Total Organic Solids (TOS) are removed from the final foods in two processes, the dietary exposure to the food enzyme-TOS was estimated for the remaining six food manufacturing processes. It was estimated to be up to 0.108 mg TOS/kg body weight per day in European populations. Based on the new data, the revised dietary exposure and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.

Authors

Publication Details

Journal
EFSA Journal
Published
2026-05-01
DOI
https://doi.org/10.2903/j.efsa.2026.10087
Primary Topic
Agricultural safety and regulations
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Safety evaluation of an extension of use of the food enzyme α‐amylase from the genetically modified Bacillus licheniformis strain NZYM‐BC

Francesco Catania, Irene Bonino, José Manuel Barat Baviera, Laurence Vernis et al.
EFSA Journal
Agricultural safety and regulations
article

Safety evaluation of an extension of use of the food enzyme α‐amylase from the genetically modified Bacillus licheniformis strain NZYM‐BC

Francesco Catania, Irene Bonino, José Manuel Barat Baviera, Laurence Vernis, Daniele Cavanna, Baltasar Mayo, Henk Van Loveren, Holger Zorn, Claudia Bolognesi, Ralf Greiner, Alicja Mortensen, Gabriele Gadermaier, Yi Liu, Marize L. M. Solano, Yrjö Henrik Roos, EFSA Panel on Food Enzymes (FEZ)
article en

Abstract

strain NZYM-BC by Novozymes A/S. The safety of this food enzyme was evaluated previously and it did not give rise to safety concerns when used in six food manufacturing processes. Subsequently, the applicant has requested to extend its use to include two additional processes and to extend, for one intended use, the range of raw materials to which the food enzyme may be added. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of eight food manufacturing processes. As the food enzyme-Total Organic Solids (TOS) are removed from the final foods in two processes, the dietary exposure to the food enzyme-TOS was estimated for the remaining six food manufacturing processes. It was estimated to be up to 0.108 mg TOS/kg body weight per day in European populations. Based on the new data, the revised dietary exposure and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.

EFSA JournalVol. 24(5)
Openalex Percentile: Top 8%
Agricultural safety and regulations
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.