Case Report of an Infectious Aortic Aneurysm Following Intravesical Bacillus Calmette‐Guérin Therapy After Transurethral Resection of a Bladder Tumor

Introduction: Intravesical Bacillus Calmette-Guérin (BCG) therapy is an established treatment for non-muscle-invasive bladder cancer. Although systemic BCG infection is rare, infectious aortic aneurysm is a potentially fatal complication. Case Presentation: BCG infection. Despite antituberculosis therapy, aneurysmal rupture with abscess progression occurred, necessitating prosthetic graft replacement with omental flap coverage. The patient recovered without recurrence after prolonged therapy. Conclusion: BCG-related infectious aortic aneurysm may develop even in the absence of fever or marked inflammatory response. Clinicians should suspect and consider early CT evaluation in patients with a history of intravesical BCG therapy when unexplained retroperitoneal or vascular abnormalities are identified, regardless of inflammatory status.

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Publication Details

Journal
IJU Case Reports
Published
2026-05-01
DOI
https://doi.org/10.1002/iju5.70176
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
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article

Case Report of an Infectious Aortic Aneurysm Following Intravesical Bacillus Calmette‐Guérin Therapy After Transurethral Resection of a Bladder Tumor

Yasushi Mochizuki, Tsuyoshi Matsuda, Kyohei Araki, Yuichiro Nakamura et al.
IJU Case Reports
Bladder and Urothelial Cancer Treatments
article

Case Report of an Infectious Aortic Aneurysm Following Intravesical Bacillus Calmette‐Guérin Therapy After Transurethral Resection of a Bladder Tumor

Yasushi Mochizuki, Tsuyoshi Matsuda, Kyohei Araki, Yuichiro Nakamura, Shintaro Mori, Tomohiro Matsuo, Kensuke Mitsunari, Ryoichi Imamura, Kojiro Ohba, Daisuke Muto
article en

Abstract

Introduction: Intravesical Bacillus Calmette-Guérin (BCG) therapy is an established treatment for non-muscle-invasive bladder cancer. Although systemic BCG infection is rare, infectious aortic aneurysm is a potentially fatal complication. Case Presentation: BCG infection. Despite antituberculosis therapy, aneurysmal rupture with abscess progression occurred, necessitating prosthetic graft replacement with omental flap coverage. The patient recovered without recurrence after prolonged therapy. Conclusion: BCG-related infectious aortic aneurysm may develop even in the absence of fever or marked inflammatory response. Clinicians should suspect and consider early CT evaluation in patients with a history of intravesical BCG therapy when unexplained retroperitoneal or vascular abnormalities are identified, regardless of inflammatory status.

IJU Case ReportsVol. 9(3)
Nagasaki University (JP)
Good health and well-being
Openalex Percentile: Top 8%
Bladder and Urothelial Cancer Treatments
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