Recurrence of Prosthetic Aortic Valve Endocarditis After Percutaneous Mechanical Aspiration

BACKGROUND: Prosthetic valve endocarditis is a dreaded complication after transcatheter aortic valve replacement, especially in older patients with multiple comorbidities, who are poor surgical candidates. We describe a case of prosthetic aortic valve endocarditis in a patient who underwent percutaneous mechanical aspiration (PMA) and its sequelae over the following year. CASE SUMMARY: The patient presented with fever and chills after flu and respiratory syncytial virus vaccines and was found to have positive blood cultures for methicillin-resistant Staphylococcus aureus and bioprosthetic aortic valve endocarditis. He was a poor surgical candidate and underwent PMA with an AngioVac device with the development of a perivalvular abscess and pericardial effusion on subsequent admissions. DISCUSSION: PMA is increasingly being used for the treatment of endocarditis, especially right sided, but there is limited evidence on its use in left-sided endocarditis due to high risk of complications. TAKE-HOME MESSAGE: There is a high risk of complications with PMA in left-sided endocarditis, but it can be used as salvage therapy in poor surgical candidates.

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Publication Details

Journal
JACC Case Reports
Published
2026-05-01
DOI
https://doi.org/10.1016/j.jaccas.2026.108143
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
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article

Recurrence of Prosthetic Aortic Valve Endocarditis After Percutaneous Mechanical Aspiration

Sampada Kuwar, Sriveni Tangellapelli, Koteswara Pothineni, Raja Saravanan et al.
JACC Case Reports
Infective Endocarditis Diagnosis and Management
article

Recurrence of Prosthetic Aortic Valve Endocarditis After Percutaneous Mechanical Aspiration

Sampada Kuwar, Sriveni Tangellapelli, Koteswara Pothineni, Raja Saravanan, Kubiat Udoh
article en

Abstract

BACKGROUND: Prosthetic valve endocarditis is a dreaded complication after transcatheter aortic valve replacement, especially in older patients with multiple comorbidities, who are poor surgical candidates. We describe a case of prosthetic aortic valve endocarditis in a patient who underwent percutaneous mechanical aspiration (PMA) and its sequelae over the following year. CASE SUMMARY: The patient presented with fever and chills after flu and respiratory syncytial virus vaccines and was found to have positive blood cultures for methicillin-resistant Staphylococcus aureus and bioprosthetic aortic valve endocarditis. He was a poor surgical candidate and underwent PMA with an AngioVac device with the development of a perivalvular abscess and pericardial effusion on subsequent admissions. DISCUSSION: PMA is increasingly being used for the treatment of endocarditis, especially right sided, but there is limited evidence on its use in left-sided endocarditis due to high risk of complications. TAKE-HOME MESSAGE: There is a high risk of complications with PMA in left-sided endocarditis, but it can be used as salvage therapy in poor surgical candidates.

JACC Case Reports
University of Tennessee Health Science Center (US), Baton Rouge General (US)
Zero hunger
Openalex Percentile: Top 6%
Infective Endocarditis Diagnosis and Management
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