Antimicrobial susceptibility trends of WHO critical Gram-negative pathogens in Fijian Hospitals, 2016–2021

Introduction: Understanding antimicrobial susceptibility patterns is essential for guiding clinical management and informing surveillance strategies. This study aimed to analyse antimicrobial susceptibility trends of WHO-designated critical Gram-negative pathogens in Fijian hospitals. Methods: isolated from three hospitals in Fiji from 1 January 2016 to 31 December 2021. Data were stratified by hospital, hospital setting, and specimen type. Only the first isolate per patient was included. Chi-square tests and linear regression were used to assess group differences and temporal trends. Results: . Conclusions: These findings highlight substantial AMR challenges in Fijian hospitals, including declining carbapenem susceptibility and high ceftriaxone resistance, underscoring the need for strengthened antimicrobial stewardship, infection control, and surveillance systems.