Impact of Continuous Nursing Intervention Delivered via Internet+ Platform on Inflammatory Responses in Ulcerative Colitis Patients

Objective: To explore the application effect of continuity nursing intervention based on the “Internet +” platform in patients with ulcerative colitis (UC) and analyze its impact on patients’ inflammatory responses. Methods: A retrospective analysis was conducted on the clinical data of 300 patients with ulcerative colitis who were treated in our hospital from February 1, 2022, to October 1, 2024. According to the difference in nursing modes, the patients were divided into a control group (150 cases) and an observation group (150 cases). The control group received conventional nursing, while the observation group received continuity nursing intervention based on the “Internet +” platform. The inflammatory responses (serum interleukin-17, IL-17; interleukin-23, IL-23; interleukin-25, IL-25) and quality of life indicators were compared between the two groups. Results: The baseline data of the two groups were comparable with no significant difference, P> 0.05. In terms of inflammatory response, the serum levels of IL-17 and IL-23 in the observation group were significantly lower than those in the control group, while the level of IL-25 was significantly higher than that in the control group (P< 0.05). The compliance rates of various indicators of treatment compliance in the observation group were significantly higher than those in the control group (P< 0.05). In addition, the anxiety and depression scores of the observation group patients were significantly lower than those of the control group, and the scores of the psychological quality scale were better than those of the control group. The ESCA, IBD-SES, and IBDQ scores were significantly higher than those of the control group (P< 0.05). Conclusion: Continuity nursing intervention based on the “Internet +” platform can significantly improve the intervention effect in patients with ulcerative colitis, associated with improved inflammatory markers, enhance treatment adherence, self-care ability and self-efficacy, and improve patients’ psychological well-being and quality of life. It is worthy of promotion. Keywords: ulcerative colitis, Internet +, continuity nursing, inflammatory response, quality of life