Orobanche cumana KAI2d2 mediates perception of dehydrocostus lactone and strigolactones and is inhibited by triazole ureas

SHORT SUMMARY: Seed germination of the parasitic plant Orobanche cumana is induced by host-derived strigolactones and dehydrocostus lactone. We show that the KAI2d2 receptor perceives both ligands through distinct modes of interaction. Triazole urea compounds covalently inhibit KAI2d receptors, suppressing germination without affecting sunflower growth.

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Publication Details

Journal
Plant Communications
Published
2026-05-01
DOI
https://doi.org/10.1016/j.xplc.2026.101889
Primary Topic
Plant Parasitism and Resistance
Type
article
Field-Weighted Citation Impact
0.00

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article

Orobanche cumana KAI2d2 mediates perception of dehydrocostus lactone and strigolactones and is inhibited by triazole ureas

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Orobanche cumana KAI2d2 mediates perception of dehydrocostus lactone and strigolactones and is inhibited by triazole ureas

Stefan T. Arold, Yoshimoto Saito, Kawthar Alashoor, Aparna Balakrishna, Muhammad Jamil, Umar F. Shahul Hameed, Salim Al-Babili, Tadao Asami, Randa Zarban
article en

Abstract

SHORT SUMMARY: Seed germination of the parasitic plant Orobanche cumana is induced by host-derived strigolactones and dehydrocostus lactone. We show that the KAI2d2 receptor perceives both ligands through distinct modes of interaction. Triazole urea compounds covalently inhibit KAI2d receptors, suppressing germination without affecting sunflower growth.

Plant Communications
Shimizu (Japan) (JP), King Abdullah University of Science and Technology (SA), The University of Tokyo (JP)
King Abdullah University of Science and Technology
Zero hunger
Openalex Percentile: Top 9%
Plant Parasitism and Resistance
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