ABSTRACT NUMBER: ESOC2026A2154 A CLINICO-EPIDEMIOLOGICAL PROFILE OF STROKE PATIENTS IN A TERTIARY CARE INSTITUTE OF NORTH INDIA

Abstract Background and aims Stroke is a leading cause of mortality and morbidity worldwide, but epidemiological data from India is limited. This study aims to study the clinico-epidemiological profile of stroke in a tertiary institute of North India. Methods All stroke patients admitted to neurology between January 2023 and March 2025 were included. The demographic profile, risk factors, clinical features, type/extent of stroke and outcome were noted. Outcome was assessed with modified Rankins score (mRS) at discharge, with mRS 4-6 poor outcome. Predictors of poor outcome were calculated. Statistical analysis was carried out using SPSS software. Results The study included 346 patients, aged 3-97 years (55.88±16.91) with 218 (63%) males. Ischemic stroke was most common(58.1%) followed by hemorrhagic stroke (37.5) and venous stroke (4.4%). Nearly 63 (18.2%) patients had recurrent stroke. GCS score at admission was 12.47±3.22 (3-15). Ischemic stroke was most commonly due to atherosclerosis (65.8%),and 17.1% were cardioembolic, 6% tuberculous meningitis-related, 5% secondary to vasculitis and 3.5% cryptogenic. The most common sites of hemorrhagic stroke were putamen (45.3%), followed by thalamus (24.2%), lobar(14.1%), cerebellum (6.3%), brainstem (6.3%), caudate (3.1%) and primary intraventricular(0.8%). Nearly 70% had hypertension, 34.6% diabetes and 6.4% rheumatic heart disease. 23 patients had atrial fibrillation. 32(9.2%) patients died, while 31% had good outcome (mRS 0-3). GCS<9, male sex, age>60 years, high leucocyte counts, high HbA1c and comorbidities were predictors of poor outcome. Poor GCS, older age and comorbidities were independent predictors of poor outcome. Conclusions Nearly 37% patients had hemorrhagic stroke, and overall mortality was 9.2%. Conflict of interest "Vinita Elizabeth Mani: nothing to disclose" "Ankita Mishra: nothing to disclose" "Akshat Kumar Srivastava: nothing to disclose" "Pooja Chaurasia: nothing to disclose" Figure 1 - belongs to Results