Efficacy and Safety of a Dual‐Wavelength 589/1319 nm Laser for the Treatment of Acne Erythema: A Split‐Face Randomized Controlled Trial

BACKGROUND: The 589/1319 nm solid-state dual-wavelength (SSDW) laser, which targets cutaneous vasculature, may be an effective treatment for acne erythema (AE). OBJECTIVES: To compare the efficacy and safety of the 589/1319 nm SSDW laser with topical soothing Aloe vera (AV) gel for the treatment of AE. PATIENTS AND METHODS: Thirty patients with bilateral AE were enrolled. One facial side received 6 sessions of 589/1319 nm SSDW laser treatment, while the contralateral side was treated with twice-daily AV gel for 18 weeks. Patients were followed for 8 weeks after the final laser session. AE severity, acne severity, and adverse events were assessed. RESULTS: = 0.47, p = 0.03). Patients reported higher satisfaction with laser treatment up to 4 weeks after the final laser session. Average pain score for the laser treatment was 1.52 out of 10. No serious adverse events were observed. CONCLUSIONS: The 589/1319 nm SSDW laser may be an effective early adjunctive treatment for acne erythema, offering minimal discomfort with no downtime and may additionally improve acne severity.