ABSTRACT NUMBER: ESOC2026YS215 PHYSICAL, PSYCHOLOGICAL, COGNITIVE AND QUALITY OF LIFE OUTCOMES AFTER CERVICAL ARTERY DISSECTION COMPARED WITH STROKE PATIENTS

Abstract Background and aims The long-term risk of psychological sequelae in patients with cervical artery dissection (CeAD) are substantial, and further interventions are warranted. However, data on psychological and quality of life outcomes in patients with CeAD compared with stroke remain limited. This cross-sectional analysis (1–2 years post-event) is conducted within an ongoing registry-based study that follows patients with stroke and CeAD for up to 10 years, with the aim of gaining a more thorough understanding of life after stroke or CeAD. Methods To provide a comprehensive comparison between patient groups, outcomes included cognitive function (MMSE), comorbidity burden (CCI), disability (mRS), health-related quality of life (EQ-5D-5L), depressive symptoms (PHQ-9), and stroke severity (NIHSS, SSS). Additionally, analyses include demographic, socioeconomic, and lifestyle-related risk factors. The study has a cross-sectional design, with follow-up conducted between 1 and 2 years after the index event. Results To date, follow-up data have been collected from 17 patients with cervical artery dissection and more than 55 patients with stroke. Final follow-up is expected to be completed by mid-February, with data analysis planned shortly thereafter. Conflict of interest August Andreasen: nothing to disclose, David Bach-Nielsen: nothing to disclose, Katrine Sværke: Nothing to disclose, Hanne Christensen: Hanne Christensen has within the last two years received honoraria for educational services from Boehringer-Ingenheim, BMS, Bayer, Covidien, Amgen and Institut for Rational Farmakoterapi; for participation in international advisory boards from Amgen and Astra Zeneca.