Argon plasma coagulation for angiokeratoma of Fordyce: a four-patient case series highlighting efficacy, safety, and cosmetic outcomes

Angiokeratoma of Fordyce is a benign vascular proliferation localized to the genitalia, often presenting with bleeding or cosmetic concerns. Treatment options vary in efficacy and side effects. To assess the clinical efficacy, safety, and cosmetic outcome of argon plasma coagulation (APC) in the treatment of angiokeratoma of Fordyce, we report a case series of four patients (three males and one female) with clinically diagnosed angiokeratoma of Fordyce, treated using APC under local anesthesia. APC parameters and postprocedure outcomes were recorded. Follow-up was conducted over 8 weeks to evaluate healing, adverse events, and recurrence. All patients achieved complete lesion resolution with excellent cosmetic outcomes and no recurrence or adverse effects within the follow-up period. The procedure was well-tolerated and required minimal downtime. APC represents a safe, effective, and cosmetically favorable option for managing angiokeratoma of Fordyce, particularly in settings lacking laser equipment.