Associations of Mitochondrial Heteroplasmy in Blood Monocytes with Its Phenotypic Indices and Cardiometabolic Parameters in Metabolic Syndrome: A Pilot Cross-sectional Study

Mitochondrial DNA (mtDNA) variability, especially heteroplasmy, is believed to affect cellular immunobiogenesis, particularly in monocytes in metabolic syndrome (MetS). This study aimed to identify associations of monocytic mtDNA variability with its phenotypic indices, including cytokine secretion and gene expression, and cardiometabolic parameters in patients with MetS.