ABSTRACT NUMBER: ESOC2026A950 CORRELATION BETWEEN MEASURED AND ESTIMATED PULSE WAVE VELOCITY IN PATIENTS WITH ACUTE ISCHEMIC STROKE

Abstract Background and aims Pulse wave velocity (PWV) is a validated marker of arterial stiffness, an important predictor of cardiovascular risk, and an independent prognostic factor after ischemic stroke. Estimated PWV (ePWV), derived from age and mean blood pressure (MBP), offers a simple alternative to direct PWV measurement. This study aimed to evaluate the correlation between directly measured PWV and ePWV in acute ischemic stroke patients. Methods Two hundred ischemic stroke patients admitted within 24 hours of symptom onset were included. Direct PWV measurement was performed on day 5 of hospitalization. Estimated PWV was calculated as follows: e1-PWV = 9.58748315543126−0.402467539733184×age+4.56020798207263×10-3×age2−2.6207705511664×10-5×age2×MBP+3.1762450559276×10-3×age×MBP−1.83215068503821×10-2×MBP; e2-PWV = 4.62−0.13×age+0.0018×age2+0.0006×age×MBP+0.0284×MBP. Data are presented as median (interquartile range). Pearson’s correlation coefficient was used for statistical analysis. Results Median PWV was 9.7 m/s (8.1–12.3 m/s), median e1-PWV 10.3 m/s (9.0–11.9 m/s), and median e2-PWV 10.3 m/s (9.1–11.7 m/s). Measured PWV showed a significant moderate correlation with e1-PWV (r=0.560, p<0.001) and e2-PWV (r=0.563, p<0.001). Conclusions Estimated PWV calculated using both equations shows a significant moderate correlation with directly measured PWV in acute ischemic stroke patients, supporting its potential clinical utility as an accessible marker of arterial stiffness. Conflict of interest Kamil Kowalczyk: nothing to disclose. Krzysztof Narkiewicz: nothing to disclose. Bartosz Karaszewski: nothing to disclose. Dariusz Gąsecki: nothing to disclose