ABSTRACT NUMBER: ESOC2026A1893 PREVALENCE AND PREDICTORS OF ISCHEMIC LESIONS IN A MULTI-ETHNIC POPULATION WITH SPONTANEOUS INTRACEREBRAL HEMORRHAGE

Abstract Background and aims ICH is the second most common type of stroke and is associated with high prevalence and mortality. Ischemic lesions have been described in patients with ICH; however, their prevalence and predictive factors in multi-ethnic populations are not well established, and studies in the Brazilian population are lacking Methods This transversal study included patients consecutively admitted with a diagnosis of ICH between January 2009 and December 2018 at a tertiary hospital. Multivariable logistic regression analysis was performed to identify independent predictors Results Eighty-nine patients were evaluated (mean age 61 ± 16.6 years), and 47 (52.8%) were female. The prevalence of ischemic lesions was 27%. Hypertension (39.8%) and Amyloid Angiopathy (AA) (29.5%) were the most frequent etiologies. Independent predictors of ischemia on MRI were AA (OR 12.8, 95%CI 2.6–91.6), intraventricular hemorrhage (OR 19.5, 95%CI 3.9–136), superficial cortical siderosis (OR 15.8, 95%CI 2.0–194), SBP 48 hours after ICH (OR 1.04, 95%CI 1.01–1.07), and ICH volume at admission (OR 0.98, 95%CI 0.95–1.0). Predictors of poor outcome included antithrombotic therapy, hematoma expansion, and ICH volume at admission. Glasgow Coma Scale score was the only predictor of in-hospital mortality. Patients with ischemic lesions had longer hospital and ICU stays Conclusions Ischemic lesions were frequent in patients with ICH. No association was found between ischemic lesions and clinical outcomes or in-hospital mortality Conflict of interest Luiz Dalfior Junior : nothing to disclose; Eva Rocha : nothing to disclose; Maramelia Miranda: nothing to disclose; Feres Chaddad Neto: nothing to disclose; Gisele Sampaio: nothing to disclose