ABSTRACT NUMBER: ESOC2026A1714 CONTROLLING NUTRITIONAL STATUS SCORE AS A PREDICTOR OF PROGNOSIS IN ACUTE STROKE PATIENTS UNDERGOING ENDOVASCULAR TREATMENT

Abstract Background and aims Malnutrition is prevalent across diseases. This study explored the correlation between Controlling Nutritional Status (CONUT) score and 90-day clinical outcomes in acute ischemic stroke (AIS) patients treated with endovascular treatment (EVT). Methods Patients were selected from the RESCUE-RE registry. The primary outcome was 90-day good prognosis (mRS 0–2), with secondary outcomes including all cause of 90-day death, early neurologic deterioration (END), symptomatic intracranial hemorrhage (sICH) and in-hospital complications. Patients were stratified by CONUT score (low: 0–4; high: 5–12). Cox proportional hazards models calculated HRs and 95% CIs. Results Among 1611 patients (male, 67.6%; Mean age, 63.98±12.16 years), 39.4% (634/1611) of patients had good outcome at 90 days (mRS 0-2). The baseline median NIHSS score was 15(11-19), and 79.07% (1269/1611) patients received full recanalization after EVT. The median CONUT score was 3(2-4). Patients were divided into two groups, low scores group of CONUT score (0-4) and higher scores group (5-12). 1235(76.66%) patients got low CONUT score and 376(23.34%) got high score. Patients in the poor clinical outcome group had higher CONUT score. Compared with High CONUT score (5-12), patients in the low CONUT score group (0-4) had higher rate of good clinical outcome at 90 days, lower rate of 90-day death, early neurological deterioration (END), pneumonia and urinary tract infection during hospitalization. Conclusions High CONUT score may be independently associated with poor 90-day outcomes in AIS-EVT patients, and could serve as a potential valuable prognostic indicator. Conflict of interest Xin Liu.nothing to disclose; Minghua Wang. nothing to disclose; ; Liping Liu.nothing to disclose.