Enhancement of Skin Barrier Function Using <scp>DYNAMiQ</scp> Technology: A Clinical Evaluation

BACKGROUND: The integrity of the skin barrier is fundamental to maintaining overall skin health, serving as the primary defense against environmental insults. Disruption of this barrier is linked to various dermatological issues, including inflammation, sensitivity, and premature aging. Therefore, technologies designed to reinforce the skin barrier and enhance moisture retention hold a significant promise for improving skin condition, resilience, and overall function. AIMS: To evaluate the restorative effect of DYNAMiQ technology on skin barrier function. METHODS: This prospective, single-center study enrolled 24 female subjects (n = 24, 26-64 years). Each subject received one DYNAMiQ treatment, with a follow-up assessment performed 7 days later. Transepidermal water loss (TEWL) was measured before treatment, immediately after, and at follow-up. Subject-reported outcomes were collected using comfort and satisfaction questionnaires, and standardized photographs were taken. RESULTS: /h, representing an 80.3% improvement in water vapor loss. All subjects (100%) expressed satisfaction with the results, and 96% reported that their skin felt more hydrated and nourished. CONCLUSIONS: DYNAMiQ technology effectively improves skin barrier function by significantly reducing TEWL. These findings are supported by high subject satisfaction and perceived hydration improvements.

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Publication Details

Journal
Journal of Cosmetic Dermatology
Published
2026-05-01
DOI
https://doi.org/10.1111/jocd.70889
Primary Topic
Advancements in Transdermal Drug Delivery
Type
article
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article

Enhancement of Skin Barrier Function Using DYNAMiQ Technology: A Clinical Evaluation

C I Salavastru, Klaus Fritz, Mariya Genova
Journal of Cosmetic Dermatology
Advancements in Transdermal Drug Delivery
article

Enhancement of Skin Barrier Function Using DYNAMiQ Technology: A Clinical Evaluation

C I Salavastru, Klaus Fritz, Mariya Genova
article en

Abstract

BACKGROUND: The integrity of the skin barrier is fundamental to maintaining overall skin health, serving as the primary defense against environmental insults. Disruption of this barrier is linked to various dermatological issues, including inflammation, sensitivity, and premature aging. Therefore, technologies designed to reinforce the skin barrier and enhance moisture retention hold a significant promise for improving skin condition, resilience, and overall function. AIMS: To evaluate the restorative effect of DYNAMiQ technology on skin barrier function. METHODS: This prospective, single-center study enrolled 24 female subjects (n = 24, 26-64 years). Each subject received one DYNAMiQ treatment, with a follow-up assessment performed 7 days later. Transepidermal water loss (TEWL) was measured before treatment, immediately after, and at follow-up. Subject-reported outcomes were collected using comfort and satisfaction questionnaires, and standardized photographs were taken. RESULTS: /h, representing an 80.3% improvement in water vapor loss. All subjects (100%) expressed satisfaction with the results, and 96% reported that their skin felt more hydrated and nourished. CONCLUSIONS: DYNAMiQ technology effectively improves skin barrier function by significantly reducing TEWL. These findings are supported by high subject satisfaction and perceived hydration improvements.

Journal of Cosmetic DermatologyVol. 25(5)
Carol Davila University of Medicine and Pharmacy (RO), Medical University Plovdiv (BG), University of Koblenz and Landau (DE), Spitalul Clinic Colentina (RO)
Clean water and sanitation
Openalex Percentile: Top 10%
Advancements in Transdermal Drug Delivery
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Enhancement of Skin Barrier Function Using <scp>DYNAMiQ</scp> Technology: A Clinical Evaluation — C I Salavastru, Klaus Fritz, et al. · Journal of Cosmetic Dermatology (2026) | TGRS Research Map | TGRS