Persistent primitive trigeminal artery cavernous sinus fistula coexisting with left vertebral artery dissecting aneurysm: A case report

A 41-years-old woman presented with left-sided headache, diplopia, and ptosis of the left eyelid. Cerebral computed tomography angiography revealed a left persistent primitive trigeminal artery cavernous sinus fistula and a dissecting aneurysm in the V4 segment of the left vertebral artery. Digital subtraction angiography confirmed the diagnosis. The fistula was successfully occluded using dual-microcatheter coil embolization combined with Onyx-18 injection, assisted by balloon protection of the internal carotid artery. The vertebral artery dissecting aneurysm was managed conservatively by administering dual antiplatelet therapy (aspirin (100 mg/day) and clopidogrel (75 mg/day) for 3 months). Follow-up imaging at 11 months demonstrated complete resolution of the aneurysm.

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Publication Details

Journal
Journal of International Medical Research
Published
2026-05-01
DOI
https://doi.org/10.1177/03000605261445219
Primary Topic
Vascular Malformations Diagnosis and Treatment
Type
article
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article

Persistent primitive trigeminal artery cavernous sinus fistula coexisting with left vertebral artery dissecting aneurysm: A case report

Rui-shu Jiang, Shi-Jie Wen, Cheng-Cai Wen
Journal of International Medical Research
Vascular Malformations Diagnosis and Treatment
article

Persistent primitive trigeminal artery cavernous sinus fistula coexisting with left vertebral artery dissecting aneurysm: A case report

Rui-shu Jiang, Shi-Jie Wen, Cheng-Cai Wen
article en

Abstract

A 41-years-old woman presented with left-sided headache, diplopia, and ptosis of the left eyelid. Cerebral computed tomography angiography revealed a left persistent primitive trigeminal artery cavernous sinus fistula and a dissecting aneurysm in the V4 segment of the left vertebral artery. Digital subtraction angiography confirmed the diagnosis. The fistula was successfully occluded using dual-microcatheter coil embolization combined with Onyx-18 injection, assisted by balloon protection of the internal carotid artery. The vertebral artery dissecting aneurysm was managed conservatively by administering dual antiplatelet therapy (aspirin (100 mg/day) and clopidogrel (75 mg/day) for 3 months). Follow-up imaging at 11 months demonstrated complete resolution of the aneurysm.

Journal of International Medical ResearchVol. 54(5)
Longyan University (CN)
Good health and well-being
Openalex Percentile: Top 8%
Vascular Malformations Diagnosis and Treatment
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Persistent primitive trigeminal artery cavernous sinus fistula coexisting with left vertebral artery dissecting aneurysm: A case report — Rui-shu Jiang, Shi-Jie Wen, et al. · Journal of International Medical Research (2026) | TGRS Research Map | TGRS