ABSTRACT NUMBER: ESOC2026OT40 OUTCOMES OF RESCUE STENTING AND ANGIOPLASTY IN ISCHEMIC STROKE FROM A MULTICENTER RETROSPECTIVE COHORT IN RIYADH, KSA

Abstract Background and aims Mechanical thrombectomy (MT) is the standard of care for large-vessel occlusion stroke; however, 10–20% of patients experience failed or incomplete recanalization due to intracranial atherosclerotic disease, refractory thrombus, or vessel injury. In such cases, rescue stenting and/or angioplasty may restore vessel patency and improve outcomes. Although preliminary studies suggest favorable recanalization and acceptable safety profiles, uncertainties remain regarding hemorrhagic risk, antiplatelet requirements, and predictors of treatment success in real-world clinical populations. Methods To evaluate the effectiveness of rescue stenting and/or angioplasty following unsuccessful MT, and to assess functional outcomes, complication rates, and predictors of favorable angiographic and clinical results. Results This retrospective multicenter cohort study will include adult patients with acute ischemic stroke due to large-vessel occlusion who underwent MT with incomplete recanalization and subsequently received rescue stenting and/or angioplasty. Clinical, imaging, and procedural variables, reperfusion status, and follow-up outcomes will be collected from participating comprehensive stroke centers. Multivariable analyses will be used to identify predictors of successful reperfusion and functional recovery. Conclusions The primary outcome is functional independence at 90 days (mRS 0–2). Secondary outcomes include successful reperfusion (mTICI 2b–3), symptomatic intracranial hemorrhage, in-stent restenosis, and 90-day mortality. Conflict of interest